BLOOD TESTING
ALL blood collected by the Western Kentucky
Regional Blood Center undergoes a variety of tests
performed by our lab technologists to ensure it is safe
for transfusion. These tests include:
1. Test for ABO Group and Rh Type- Although there
are more than 400 substances (known as red cell antigens)
on red blood cells, the ABO group and Rh type are
considered to be the most important with regard to blood
transfusion. This test identifies each donor's blood type
( O, A, B, or AB) and Rh type (Positive or negative),
enabling future patient matching.
2. Test for Unexpected Antibodies- It is possible
that a person who has been transfused or pregnant may have
produced what are referred to as unexpected antibodies as
a result of exposure to red cell antigens that are
"foreign" to his/her immune system. Even if unexpected
antibodies are detected, the red blood cells may be used
for transfusion because the antibody-containing plasma can
be separated from the red cells.
3. Test for Syphilis- Exposure to syphilis causes
the production of antibodies for Treponema Pallidum (the
spirochete that causes syphilis). The RPR test detects the
presence of these antibodies. Even though this organism
does not survive after three days in units of blood stored
at refrigerator temperatures, this test is required by the
FDA
4. Test for Hepatitis B Surface Antigen (HBsAg) -
HBsAg testing is performed to help prevent transmission of
hepatitis B to blood recipients. The complex hepatitis B
virus produces several different substances known as viral
antigens. The surface antigen is the one for which all
blood donors are tested. Its presence indicates that a
person may be a carrier and is infectious.
5. Test for Hepatitis B Core Antibody (Anti-HBc) -
"Core" testing is performed to detect possible past
exposure to hepatitis B.
6. Combination Test for HIV I/II Antibodies - This
test is performed to prevent transmission of HIV by
transfusion. Exposure to HIV results in the production of
HIV antibodies, which are detected by the test. THIS IS
NOT A DIAGNOSTIC TEST FOR AIDS. The diagnosis of AIDS can
only be made by other laboratory tests as well as
physician's evaluation.
7. Test for HTLV I-II Antibody - This test detects
antibodies to a virus called Human T-Lymphotropic Virus
type I and HTLV type II that is linked to adult T-cell
leukemia and progressive neurological disease. These
diseases are mostly found in Japan and the Caribbean
countries, and are rarely seen in the United States.
8. Test for Hepatitis C (HCV) Antibody - This test
is another tool in the ongoing efforts directed against
transfusion-transmitted hepatitis C. Although the test is
not diagnostic, it is a useful screening test that can
detect the proteins that develop in one's blood when
exposed to to hepatitis C virus.
9. Nucleic Acid Testing (NAT) for HIV and HCV-
These tests detect very low numbers of viral copies after
they appear in the bloodstream.
These tests take approximately eight (6) hours per unit of
blood to complete. All units of blood found to be positive
are destroyed and those donors are confidentially
contacted.
A single donation can help save at least three (3)
patients. Nearly all blood collected by the Western
Kentucky Regional Blood Center is separated into
components such as red blood cells, platelets and fresh
frozen plasma.
By separating blood into components, patients receive only
the component needed to treat their particular illness or
injury. Whole blood (donated for oneself) must be used
within thirty-five (35) days from the collection date;
Leukocyte reduced packed red cells must be used with in
forty-two (42) days; platelets with in five (5) days; and
fresh froze plasma within one year. the shelf life of the
blood is another reason the Western Kentucky Regional
Blood Center needs and depends on caring individuals of
our community to donate regularly.
Western Kentucky Regional Blood Center is inspected and
accredited by the Food and Drug Administration (FDA), CLIA, and the State of
Kentucky.
Western Kentucky Regional Blood Center is a member of the
American Association of Blood Banks, the Kentucky
Association of Blood Banks and the America's Blood
Centers.
Western Kentucky Regional Blood Center Board of Directors
consists of administrators and pathologist of the
hospitals served.
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